Hormonal and metabolic response to hypoglycaemia in small for gestational age infants.

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Hormonal and metabolic response to hypoglycaemia in small for gestational age infants.

Little is known of the ability of hypoglycaemic infants who are small for gestational age (SGA) to mount the coordinated hormonal and metabolic counterregulatory response that is seen in healthy older subjects during glycopenia. This response was studied in 22 SGA infants (birth weight < 10th centile) by measuring the blood concentrations of glucose, intermediary metabolites, and glucoregulator...

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Metabolic adaptation in small for gestational age infants.

Hypoglycaemia has long been recognised as a feature of the failure of metabolic adaptation in infants who are small for gestational age (SGA). This study examined the process of metabolic adaptation by measuring, longitudinally, the concentrations of metabolic fuels and substrates in 33 SGA infants in the first postnatal week, and relating these to cross sectional data in 218 infants of appropr...

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Clinical and molecular characterisation of hyperinsulinaemic hypoglycaemia in infants born small-for-gestational age

OBJECTIVE To characterise the phenotype and genotype of neonates born small-for-gestational age (SGA; birth weight <10th centile) who developed hyperinsulinaemic hypoglycaemia (HH). METHODS Clinical information was prospectively collected on 27 SGA neonates with HH, followed by sequencing of KCNJ11 and ABCC8. RESULTS There was no correlation between the maximum glucose requirement and serum...

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Comparisons of mortality and pre-discharge respiratory morbidities in small for gestational age and appropriate-for gestational age premature infants - An Indian Experience

Background: There is an assumption that fetus with restricted growth with an inappropriate intrauterine environment lies under stress. Although small-for-gestational-age (SGA) infants have higher mortality, difference in the outcome of SGA and appropriate-for-gestational-age (AGA) infants regarding respiratory morbidity is controversial. It seems that respiratory morbidities in SGA neonates is ...

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Comparative Study of Cord Lipid Profile in Small for Gestational Age and Appropriate for Gestational Age Newborn

Background: This study was conducted to compare the cord blood lipid profile in term small for gestation (SGA) and appropriate for gestational age (AGA) babies as determination of cord blood lipid profile is useful screening tool for early detection of babies at higher risk as atherosclerosis has its genesis in childhood. Methods: Study Design: Hospital based cross sectional study. Setting: ne...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1993

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.68.3_spec_no.269